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A predisposition (skin patch) test for all products containing an aniline derivative ingredient is a requirement from the:

U.S. Federal Food, Drug, and Cosmetics Act

Safety testing and labeling of cosmetics in the United States are overseen by the U.S. Food and Drug Administration under the Federal Food, Drug, and Cosmetic Act. This act gives FDA authority to regulate cosmetics and require safety measures, including steps to reduce risk for products that contain reactive ingredients like aniline derivatives used in hair dyes. A predisposition skin patch test helps identify individuals who may have an allergic reaction before using the product, which aligns with FDA's goal of consumer safety in cosmetics. This kind of precaution doesn’t come from workplace safety rules (OSHA), from the older Pure Food and Drug Act, or from advertising-focused regulation (FTC). So the Federal Food, Drug, and Cosmetic Act is the source of such a requirement.

Occupational Safety and Health Act

Pure Food and Drug Act

Federal Trade Commission Act

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